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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3802
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Syp
Name: synaptophysin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sypmultiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [Oxidopamine results in decreased expression of SYP protein]PMID:34302886
Sypincreases expressionISOSYP (Homo sapiens)6480464CTDresveratrol results in increased expression of SYP mRNAPMID:18592012 PMID:21161674
Sypmultiple interactionsISOSyp (Mus musculus)6480464CTDresveratrol inhibits the reaction [PPT1 gene mutant form results in decreased expression of SYP protein]PMID:21224254
Sypmultiple interactionsISOSYP (Homo sapiens)6480464CTDpyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA]PMID:21161674
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