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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3786
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc8affects bindingEXP 6480464CTDresveratrol binds to ABCC8 proteinPMID:17138562
Abcc8increases response to substanceEXP 6480464CTDABCC8 protein results in increased susceptibility to resveratrolPMID:19095654
Abcc8multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Glyburide binds to ABCC8 protein]PMID:17138562
Abcc8multiple interactionsISOABCC8 (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of ABCC8 mRNAPMID:23557933
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