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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod3
Name: superoxide dismutase 3
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod3increases expressionEXP 6480464CTDresveratrol results in increased expression of SOD3 mRNA; resveratrol results in increased expression of SOD3 proteinPMID:24894866
Sod3multiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; resveratrol inhibits the reaction [Estradiol results in decreased expression of SOD3 protein]PMID:24894866
Sod3decreases expressionISOSOD3 (Homo sapiens)6480464CTDresveratrol results in decreased expression of SOD3 mRNAPMID:20706672
Sod3increases expressionISOSod3 (Mus musculus)6480464CTDresveratrol results in increased expression of SOD3 mRNAPMID:20610621
Sod3increases expressionISOSOD3 (Homo sapiens)6480464CTDResveratrol results in increased expression of SOD3; Resveratrol results in increased expression of SOD3 mRNA; Resveratrol results in increased expression of SOD3 proteinPMID:20610621 PMID:28960787
Sod3multiple interactionsISOSOD3 (Homo sapiens)6480464CTDresveratrol inhibits the reaction [Estradiol results in decreased expression of SOD3 mRNA]; resveratrol inhibits the reaction [Estradiol results in decreased expression of SOD3 protein]PMID:25130429
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