GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hras | affects expression | ISO | HRAS (Homo sapiens) | 6480464 | CTD | resveratrol affects the expression of HRAS mRNA mutant form; resveratrol affects the expression of HRAS protein mutant form | PMID:16369916 | Hras | multiple interactions | ISO | Hras (Mus musculus) | 6480464 | CTD | [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] | PMID:20103723 | Hras | multiple interactions | ISO | HRAS (Homo sapiens) | 6480464 | CTD | HRAS protein promotes the reaction [resveratrol results in increased activity of MAPK1 protein]; HRAS protein promotes the reaction [resveratrol results in increased activity of MAPK3 protein]; HRAS protein promotes the reaction [resveratrol results in increased expression of and results in increased phosphorylation of TP53 protein]; HRAS protein promotes the reaction [resveratrol results in increased expression of CDKN1A mRNA]; HRAS protein promotes the reaction [resveratrol results in increased expression of TP53 mRNA]; HRAS protein promotes the reaction [resveratrol results in increased phosphorylation of and results in increased localization of and results in increased activity of MAPK1 protein]; HRAS protein promotes the reaction [resveratrol results in increased phosphorylation of and results in increased localization of and results in increased activity of MAPK3 protein]; HRAS protein promotes the reaction [TP53 protein results in increased susceptibility to resveratrol] | PMID:11889192 | | ||||||||||||||||||||||
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