GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr2 | affects binding | EXP | | 6480464 | CTD | resveratrol binds to ESR2 protein | PMID:11014220 | Esr2 | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of ESR2 protein | PMID:22104698 | Esr2 | multiple interactions | EXP | | 6480464 | CTD | [2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein] inhibits the reaction [resveratrol results in decreased expression of PRL protein]; resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]; resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]; resveratrol binds to and results in increased activity of ESR2 protein; resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]; resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein] | PMID:11014220 PMID:22104698 PMID:24333797 | Esr2 | affects binding | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | resveratrol analog binds to ESR2 protein; resveratrol binds to ESR2 protein | PMID:11507064 PMID:21248286 PMID:26970359 | Esr2 | affects response to substance | ISO | Esr2 (Mus musculus) | 6480464 | CTD | ESR2 protein affects the susceptibility to resveratrol | PMID:23526725 | Esr2 | increases activity | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | resveratrol results in increased activity of ESR2 protein | PMID:16118406 PMID:17935960 | Esr2 | increases expression | ISO | Esr2 (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of ESR2 protein | PMID:17675339 | Esr2 | increases expression | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Resveratrol analog results in increased expression of ESR2 mRNA; Resveratrol analog results in increased expression of ESR2 protein; Resveratrol results in increased expression of ESR2 mRNA; Resveratrol results in increased expression of ESR2 protein | PMID:15149879 PMID:24299158 PMID:25242450 PMID:26970359 | Esr2 | multiple interactions | ISO | Esr2 (Mus musculus) | 6480464 | CTD | ESR2 gene mutant form inhibits the reaction [resveratrol results in increased expression of SOD2 protein]; ESR2 protein affects the reaction [resveratrol results in increased expression of SOD2 protein] | PMID:23526725 PMID:24361291 | Esr2 | multiple interactions | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | ESR2 protein promotes the reaction [resveratrol analog results in decreased expression of MYC protein]; fulvestrant inhibits the reaction [resveratrol results in increased activity of ESR2 protein]; resveratrol binds to and results in decreased activity of ESR2 protein; resveratrol binds to and results in increased activity of ESR2 protein; resveratrol inhibits the reaction [Estradiol binds to ESR2 protein]; resveratrol promotes the reaction [Estradiol results in increased activity of ESR2 protein] | PMID:11507064 PMID:12765243 PMID:15084758 PMID:16118406 PMID:17935960 PMID:26970359 | |
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