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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70884
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif2ak3
Name: eukaryotic translation initiation factor 2 alpha kinase 3
Acc ID: CHEBI:27869
Term: chloroacetic acid
Definition: A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
Chemical ID: MESH:C006972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2ak3increases phosphorylationISOEif2ak3 (Mus musculus)6480464CTDchloroacetic acid results in increased phosphorylation of EIF2AK3 proteinPMID:25451595
Eif2ak3multiple interactionsISOEif2ak3 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein]PMID:25451595
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