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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620525
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcl1
Name: MCL1 apoptosis regulator, BCL2 family member
Acc ID: CHEBI:27827
Term: paraoxon
Definition: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Chemical ID: MESH:D010261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcl1decreases expressionISOMcl1 (Mus musculus)6480464CTDParaoxon results in decreased expression of MCL1 polyA tailPMID:22093924
Mcl1increases expressionISOMcl1 (Mus musculus)6480464CTDParaoxon results in increased expression of MCL1 protein alternative formPMID:22093924
Mcl1multiple interactionsISOMcl1 (Mus musculus)6480464CTDACHE protein inhibits the reaction [Paraoxon results in decreased expression of MCL1 polyA tail]PMID:22093924
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