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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737474 Species: Homo sapiens RGD Object: Gene Symbol: SLC16A1 Name: solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

Acc ID: CHEBI:27732 Term: caffeine Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. CasRN: 58-08-2 Chemical ID: MESH:D002110

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Caffeine affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]	PMID:19023563
increases expression	EXP		6480464	CTD	Caffeine results in increased expression of SLC16A1 mRNA	PMID:19023563