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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:27642
Term: methyl tert-butyl ether
Definition: An ether having methyl and tert-butyl as the two alkyl components.
Chemical ID: MESH:C043243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3decreases phosphorylationEXP 6480464CTDmethyl tert-butyl ether results in decreased phosphorylation of MAPK3 proteinPMID:19344668
Mapk3multiple interactionsEXP 6480464CTDBicuculline inhibits the reaction [methyl tert-butyl ether results in decreased phosphorylation of MAPK3 protein]; Muscimol promotes the reaction [methyl tert-butyl ether results in decreased phosphorylation of MAPK3 protein]PMID:19344668
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