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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp1
Name: matrix metallopeptidase 1
Acc ID: CHEBI:27638
Term: cobalt atom
Definition: A cobalt group element atom that has atomic number 27.
Chemical ID: MESH:D003035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp1increases expressionISOMMP1 (Homo sapiens)6480464CTDCobalt results in increased expression of MMP1 mRNAPMID:15878362
Mmp1multiple interactionsISOMMP1 (Homo sapiens)6480464CTD[tungsten carbide binds to Cobalt] which results in decreased expression of MMP1 mRNA; Genistein inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]; herbimycin inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA]PMID:15878362 PMID:20105288
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