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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaaffects localizationISORela (Mus musculus)6480464CTDArsenic affects the localization of RELA proteinPMID:27289040
Reladecreases expressionISORELA (Homo sapiens)6480464CTDArsenic results in decreased expression of RELA mRNAPMID:27838757
Relamultiple interactionsISORela (Mus musculus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of RELA proteinPMID:33049506
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