GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsk3b | multiple interactions | EXP | | 6480464 | CTD | 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein; IL1RN protein inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein] | PMID:35993674 | Gsk3b | decreases expression | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Arsenic results in decreased expression of GSK3B mRNA | PMID:29107899 | Gsk3b | increases expression | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of GSK3B protein | PMID:30890376 | Gsk3b | increases phosphorylation | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Arsenic results in increased phosphorylation of GSK3B protein | PMID:22552367 | Gsk3b | increases phosphorylation | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | Arsenic results in increased phosphorylation of GSK3B protein | PMID:22552367 | Gsk3b | multiple interactions | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | GSK3B affects the susceptibility to [Fluorides co-treated with Arsenic] | PMID:30890376 | | ||||||||||||||||||||||
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