GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prkdc | decreases expression | ISO | PRKDC (Homo sapiens) | 6480464 | CTD | Arsenic results in decreased expression of PRKDC mRNA; Arsenic results in decreased expression of PRKDC protein | PMID:21332098 | Prkdc | increases expression | ISO | PRKDC (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of PRKDC protein | PMID:19818359 | Prkdc | increases response to substance | ISO | PRKDC (Homo sapiens) | 6480464 | CTD | PRKDC mRNA results in increased susceptibility to Arsenic | PMID:17976673 | Prkdc | multiple interactions | ISO | PRKDC (Homo sapiens) | 6480464 | CTD | Curcumin inhibits the reaction [Arsenic results in decreased expression of PRKDC mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PRKDC protein] | PMID:21332098 | Prkdc | multiple interactions | ISO | Prkdc (Mus musculus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of PRKDC protein | PMID:37527016 | |
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