GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ehmt2 | affects methylation | ISO | EHMT2 (Homo sapiens) | 6480464 | CTD | Arsenic affects the methylation of EHMT2 gene | PMID:25304211 | Ehmt2 | multiple interactions | ISO | EHMT2 (Homo sapiens) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with BIX 01294] results in decreased expression of EHMT2 mRNA; [[sodium arsenite results in increased abundance of Arsenic] which co-treated with BIX 01294] results in decreased expression of EHMT2 protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of MPG mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of MPG protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of PARP1 mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of PARP1 protein; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of XRCC1 mRNA; [EHMT2 protein co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of XRCC1 protein | PMID:33378118 | | ||||||||||||||||||||||
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