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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620311
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr7a2
Name: aldo-keto reductase family 7, member A2
Acc ID: CHEBI:27539
Term: isatin
Definition: An indoledione that is the 2,3-diketo derivative of indole.
Chemical ID: MESH:D007510
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr7a2affects reductionISOAkr7a5 (Mus musculus)6480464CTDIsatin affects the reduction of AKR7A5 proteinPMID:12604212
Akr7a2increases reductionISOAKR7A2 (Homo sapiens)6480464CTDAKR7A2 protein results in increased reduction of IsatinPMID:10510318
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