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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147 Species: Rattus norvegicus RGD Object: Gene Symbol: Ar Name: androgen receptor

Acc ID: CHEBI:27436 Term: methyltestosterone Definition: A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position. CasRN: 58-18-4 Chemical ID: MESH:D008777

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735652	6480464	CTD	Methyltestosterone binds to and results in increased activity of AR protein	PMID:12730620
affects binding	EXP		6480464	CTD	Methyltestosterone binds to AR protein	PMID:19833195 PMID:14565775
affects binding	EXP		6480464	CTD	Methyltestosterone binds to AR protein	PMID:14565775 PMID:19833195
multiple interactions	ISO	RGD:735652	6480464	CTD	Methyltestosterone binds to and results in increased activity of AR protein	PMID:20438827 PMID:12730620
multiple interactions	ISO	RGD:735652	6480464	CTD	Methyltestosterone binds to and results in increased activity of AR protein	PMID:12730620 PMID:20438827
affects binding	EXP		6480464	CTD	Methyltestosterone binds to AR protein	PMID:14565775 PMID:19833195 PMID:20371976