GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | JAK1 | increases expression | ISO | Jak1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of JAK1 mRNA | PMID:26062544 | JAK1 | increases phosphorylation | ISO | Jak1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased phosphorylation of JAK1 protein | PMID:28428136 | JAK1 | multiple interactions | ISO | Jak1 (Rattus norvegicus) | 6480464 | CTD | Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of JAK1 mRNA] | PMID:26062544 | JAK1 | multiple interactions | ISO | Jak1 (Mus musculus) | 6480464 | CTD | hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK1 protein]; Silymarin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of JAK1 protein] | PMID:28428136 | | ||||||||||||||||||||||
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