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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9affects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of MAPK9 mRNAPMID:16239168
Mapk9increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of MAPK9 proteinPMID:18081878
Mapk9increases phosphorylationISOMapk9 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased phosphorylation of MAPK9 proteinPMID:20589743 PMID:21291945
Mapk9multiple interactionsISOMapk9 (Mus musculus)6480464CTD[Dietary Fats co-treated with Carbon Tetrachloride] results in increased phosphorylation of MAPK9 protein; alisol B inhibits the reaction [[Dietary Fats co-treated with Carbon Tetrachloride] results in increased phosphorylation of MAPK9 protein]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK9 protein]PMID:20589743 PMID:35745142
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