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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3825
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tbxa2r
Name: thromboxane A2 receptor
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tbxa2raffects response to substanceISOTbxa2r (Mus musculus)6480464CTDTBXA2R protein affects the susceptibility to Carbon TetrachloridePMID:22206755
Tbxa2rincreases expressionISOTbxa2r (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of TBXA2R mRNAPMID:22206755
Tbxa2rmultiple interactionsISOTbxa2r (Mus musculus)6480464CTDTBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of ADGRE1 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of ADGRE1 protein]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCR2 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of CCR2 protein]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of HGF mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of ITGAM mRNA]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of ITGAM protein]; TBXA2R protein affects the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]PMID:22206755
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