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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3193
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nppa
Name: natriuretic peptide A
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppadecreases secretionEXP 6480464CTDCarbon Tetrachloride results in decreased secretion of NPPA proteinPMID:16449355
Nppaincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of NPPA mRNAPMID:16644059
Nppamultiple interactionsEXP 6480464CTDcandoxatrilat inhibits the reaction [Carbon Tetrachloride results in decreased secretion of NPPA protein]PMID:16449355
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