GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos3 | decreases activity | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased activity of NOS3 protein | PMID:12943827 | Nos3 | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of NOS3 protein | PMID:12575897 | Nos3 | decreases phosphorylation | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased phosphorylation of NOS3 protein | PMID:12891555 | Nos3 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of NOS3 mRNA; Carbon Tetrachloride results in increased expression of NOS3 protein | PMID:16325526 PMID:16644059 | Nos3 | multiple interactions | EXP | | 6480464 | CTD | AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased phosphorylation of NOS3 protein]; Carbon Tetrachloride results in decreased phosphorylation of and results in decreased activity of NOS3 protein; Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of NOS3 protein; wortmannin affects the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of NOS3 protein] | PMID:12891555 PMID:18245901 PMID:18317400 | Nos3 | decreases expression | ISO | Nos3 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of NOS3 mRNA; Carbon Tetrachloride results in decreased expression of NOS3 protein | PMID:18429990 | |
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