GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kdr | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of KDR mRNA | PMID:31150632 | Kdr | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of KDR mRNA; Carbon Tetrachloride results in increased expression of KDR protein | PMID:23845850 | Kdr | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein] | PMID:23845850 | Kdr | increases expression | ISO | Kdr (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of KDR protein | PMID:33549628 | Kdr | multiple interactions | ISO | Kdr (Mus musculus) | 6480464 | CTD | ATG5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein]]; ATG5 protein promotes the reaction [Carbon Tetrachloride results in increased expression of KDR protein]; curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein]; KLF5 protein inhibits the reaction [curcumol inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein]]; KLF5 protein promotes the reaction [Carbon Tetrachloride results in increased expression of KDR protein] | PMID:33549628 | |
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