GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Edn1 | increases activity | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased activity of EDN1 protein | PMID:25858767 | Edn1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of EDN1 mRNA; Carbon Tetrachloride results in increased expression of EDN1 protein | PMID:12575897 PMID:12632514 PMID:12708965 PMID:17595544 | Edn1 | multiple interactions | EXP | | 6480464 | CTD | Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]; EDNRB protein affects the reaction [Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor]]; IL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of EDN1 protein] | PMID:12632514 PMID:18205269 | Edn1 | increases expression | ISO | Edn1 (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of EDN1 mRNA; Carbon Tetrachloride results in increased expression of EDN1 protein | PMID:17484886 PMID:25445725 PMID:25827057 | Edn1 | multiple interactions | ISO | Edn1 (Mus musculus) | 6480464 | CTD | Lipids inhibits the reaction [Carbon Tetrachloride results in increased expression of EDN1 protein] | PMID:25445725 | |
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