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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2469
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c11
Name: cytochrome P450, subfamily 2, polypeptide 11
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c11affects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of CYP2C mRNAPMID:12734012 PMID:17805973
Cyp2c11decreases activityEXP 6480464CTDCarbon Tetrachloride results in decreased activity of CYP2C11 proteinPMID:14706259
Cyp2c11decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of CYP2C protein; Carbon Tetrachloride results in decreased expression of CYP2C11 mRNA; Carbon Tetrachloride results in decreased expression of CYP2C11 proteinPMID:12629582 PMID:14706259 PMID:17606319 PMID:30723492
Cyp2c11increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of CYP2C11 mRNAPMID:31150632
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