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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2307
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd44
Name: CD44 molecule
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd44affects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of CD44 mRNAPMID:12734012
Cd44increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of CD44 mRNA; Carbon Tetrachloride results in increased expression of CD44 proteinPMID:12629582 PMID:31150632
Cd44multiple interactionsEXP 6480464CTDschizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CD44 mRNA]PMID:31150632
Cd44increases expressionISOCd44 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of CD44 mRNAPMID:17484886 PMID:27339419 PMID:31919559
Cd44multiple interactionsISOCd44 (Mus musculus)6480464CTDCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]; CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1A mRNA]; CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]; CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of LTB mRNA]; CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]PMID:18395288
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