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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2119 Species: Rattus norvegicus RGD Object: Gene Symbol: Anxa3 Name: annexin A3

Acc ID: CHEBI:27385 Term: tetrachloromethane Definition: A chloromethane that has formula CCl4. CasRN: 56-23-5 Chemical ID: MESH:D002251

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Carbon Tetrachloride results in decreased expression of ANXA3 mRNA	PMID:16644059
increases expression	EXP		6480464	CTD	Carbon Tetrachloride results in increased expression of ANXA3 protein Carbon Tetrachloride results in increased expression of ANXA3 mRNA	PMID:18182385
multiple interactions	EXP		6480464	CTD	[Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of ANXA3 mRNA	PMID:18071240
multiple interactions	EXP		6480464	CTD	HGF protein affects the reaction [Carbon Tetrachloride results in increased expression of ANXA3 mRNA]	PMID:18182385