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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930 Species: Rattus norvegicus RGD Object: Gene Symbol: Abcb11 Name: ATP-binding cassette, subfamily B (MDR/TAP), member 11

Acc ID: CHEBI:27375 Term: vincaleukoblastine Definition: A vinca alkaloid that has formula C46H58N4O9. CasRN: 865-21-4 Chemical ID: MESH:D014747

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases uptake	ISO	RGD:730945	6480464	CTD	ABCB11 protein results in decreased uptake of Vinblastine	PMID:10617675
increases export	ISO	RGD:730945	6480464	CTD	ABCB11 protein results in increased export of Vinblastine	PMID:10617675