GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S100a9
Name: S100 calcium binding protein A9
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
CasRN: 7440-66-6
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects bindingISORGD:13529816480464CTDZinc binds to [S100A8 protein binds to S100A9 protein]

PMID:17050004
multiple interactionsISORGD:13529816480464CTD[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]

PMID:17050004
increases expressionISORGD:7331756480464CTDZinc deficiency results in increased expression of S100A9 mRNA

PMID:20857495
increases expressionEXP 6480464CTDZinc deficiency results in increased expression of S100A9 mRNA

PMID:19111725
multiple interactionsEXP 6480464CTDZinc inhibits the reaction [Zinc deficiency results in increased expression of S100A9 mRNA]

PMID:19111725
multiple interactionsISORGD:7331756480464CTD[Zinc deficiency co-treated with PTGS2 gene mutant form] results in increased expression of S100A9 mRNA

[Zinc deficiency co-treated with PTGS2 gene mutant form] results in increased expression of S100A9 protein

Zinc inhibits the reaction [[Zinc deficiency co-treated with PTGS2 gene mutant form] results in increased expression of S100A9 mRNA]

Zinc inhibits the reaction [[Zinc deficiency co-treated with PTGS2 gene mutant form] results in increased expression of S100A9 protein]

PMID:20857495
increases expressionEXP 6480464CTDZinc deficiency results in increased expression of S100A9 protein

PMID:22689922
increases expressionEXP 6480464CTDZinc deficiency results in increased expression of S100A9 mRNA

PMID:19111725
PMID:22689922
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