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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10decreases expressionEXP 6480464CTDZinc deficiency results in decreased expression of IL10 mRNAPMID:10938463
Il10decreases expressionISOIL10 (Homo sapiens)6480464CTDZinc results in decreased expression of IL10 mRNA; Zinc results in decreased expression of IL10 proteinPMID:17622302 PMID:18842795
Il10decreases secretionISOIL10 (Homo sapiens)6480464CTDZinc results in decreased secretion of IL10 proteinPMID:17150331
Il10increases expressionISOIL10 (Homo sapiens)6480464CTDZinc deficiency results in increased expression of IL10 mRNA; Zinc results in increased expression of IL10 mRNAPMID:12888634 PMID:17622302
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDN,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in decreased secretion of IL10 protein]PMID:17150331
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