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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10736 Species: Mus musculus RGD Object: Gene Symbol: Hsd17b1 Name: hydroxysteroid (17-beta) dehydrogenase 1

Acc ID: CHEBI:2710 Term: androst-5-ene-3beta,17beta-diol Definition: An androst-5-ene-based steroid with hydroxy substituents at the 3beta- and 17beta-positions. CasRN: 521-17-5 Chemical ID: MESH:D015114

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects metabolic processing	ISO	RGD:736216	6480464	CTD	HSD17B1 protein affects the metabolism of Androstenediol	PMID:16054388
increases chemical synthesis	ISO	RGD:736216	6480464	CTD	HSD17B1 protein results in increased chemical synthesis of Androstenediol	PMID:16054388