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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732061 Species: Homo sapiens RGD Object: Gene Symbol: CDK4 Name: cyclin-dependent kinase 4

Acc ID: CHEBI:27013 Term: tocopherol Definition: A collective name for a group of closely related lipids that contain substitutions on the 3,4-dihydro-2H-chromen-6-ol nucleus and a hydrocarbon chain consisting of three isoprenoid units. CasRN: 1406-66-2 Chemical ID: MESH:D024505

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein	PMID:12504091