GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TRPV1 | affects response to substance | EXP | | 6480464 | CTD | TRPV1 affects the susceptibility to anandamide | PMID:15453094 | TRPV1 | increases activity | EXP | | 6480464 | CTD | anandamide results in increased activity of TRPV1 protein | PMID:17913835 | TRPV1 | increases response to substance | EXP | | 6480464 | CTD | TRPV1 protein results in increased susceptibility to anandamide | PMID:21949157 | TRPV1 | multiple interactions | EXP | | 6480464 | CTD | 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Egtazic Acid inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; methyl arachidonylfluorophosphonate promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; N-(2-methyl-3-hydroxyphenyl)-5,8,11,14-eicosatetraenamide inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Nitroprusside promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Phenylmethylsulfonyl Fluoride promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein] | PMID:11278420 PMID:15453094 PMID:15615864 | TRPV1 | affects binding | ISO | Trpv1 (Rattus norvegicus) | 6480464 | CTD | anandamide binds to TRPV1 protein | PMID:15601931 | TRPV1 | increases activity | ISO | Trpv1 (Rattus norvegicus) | 6480464 | CTD | anandamide results in increased activity of TRPV1 protein | PMID:11140687 PMID:14504685 PMID:15601931 PMID:17038422 | TRPV1 | multiple interactions | ISO | Trpv1 (Rattus norvegicus) | 6480464 | CTD | 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; bisindolylmaleimide inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein] | PMID:11140687 PMID:15615864 PMID:17038422 PMID:18550765 | | ||||||||||||||||||||||
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