GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | oxymatrine promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein] | PMID:27713174 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | [oxymatrine co-treated with IL1B protein] results in decreased expression of NFE2L2 protein; [oxymatrine inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased stability of and results in increased localization of NFE2L2 protein; NFE2L2 protein promotes the reaction [oxymatrine inhibits the reaction [IL1B protein results in increased expression of RELA protein]]; NFE2L2 protein promotes the reaction [oxymatrine promotes the reaction [IL1B protein results in increased expression of HMOX1 protein]]; oxymatrine inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; oxymatrine promotes the reaction [IL1B protein results in increased expression of NFE2L2 protein] | PMID:37196756 | |
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