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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:26708
Term: sodium atom
Definition: An alkali metal atom that has formula Na.
Chemical ID: MESH:D012964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtdecreases exportEXP 6480464CTDAGT protein results in decreased export of SodiumPMID:14597645
Agtincreases expressionEXP 6480464CTDSodium deficiency results in increased expression of AGT proteinPMID:3028957
Agtmultiple interactionsEXP 6480464CTDacetovanillone inhibits the reaction [AGT protein results in decreased export of Sodium]; tempol inhibits the reaction [AGT protein results in decreased export of Sodium]; Valsartan inhibits the reaction [AGT protein results in decreased export of Sodium]PMID:14597645
Agtdecreases abundanceISOAGT (Homo sapiens)6480464CTDAGT protein results in decreased abundance of SodiumPMID:12869368
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