GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | decreases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Amiodarone results in decreased expression of SOD2 mRNA | PMID:34434487 | Sod2 | increases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Amiodarone results in increased expression of SOD2 mRNA; Amiodarone results in increased expression of SOD2 protein | PMID:23135547 PMID:28526448 | Sod2 | multiple interactions | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]] | PMID:34434487 | |
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