GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | increases expression | EXP | | 6480464 | CTD | Amiodarone results in increased expression of CYP1A1 mRNA | PMID:19224547 PMID:32084307 | Cyp1a1 | multiple interactions | EXP | | 6480464 | CTD | Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA] | PMID:20362646 | Cyp1a1 | decreases activity | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | Amiodarone results in decreased activity of CYP1A1 protein | PMID:33814510 PMID:34181028 | Cyp1a1 | increases response to substance | ISO | CYP1A1 (Homo sapiens) | 6480464 | CTD | CYP1A1 protein results in increased susceptibility to Amiodarone | PMID:26477383 | |
Go Back to source page | Continue to Ontology report |