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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:26523
Term: reactive oxygen species
Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Chemical ID: MESH:D017382
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDReactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]PMID:19804834
Mmp9multiple interactionsISOMmp9 (Mus musculus)6480464CTDReactive Oxygen Species affects the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]PMID:15557194
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