GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | increases abundance | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | VEGFA protein results in increased abundance of Reactive Oxygen Species | PMID:12855698 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of VEGFA mRNA; [cobaltous chloride results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of VEGFA mRNA; [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of VEGFA mRNA; CAT protein inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]; diphenyleneiodonium inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]; PAK1 protein promotes the reaction [VEGFA protein results in increased abundance of Reactive Oxygen Species] | PMID:12855698 PMID:13679210 PMID:21687637 PMID:24489904 | |
Go Back to source page | Continue to Ontology report |