GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptk2 | increases phosphorylation | ISO | PTK2 (Homo sapiens) | 6480464 | CTD | Reactive Oxygen Species results in increased phosphorylation of PTK2 protein | PMID:11213483 | Ptk2 | multiple interactions | ISO | PTK2 (Homo sapiens) | 6480464 | CTD | [[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; Anethole Trithione inhibits the reaction [Reactive Oxygen Species results in increased phosphorylation of PTK2 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein] | PMID:11213483 PMID:17888894 | |
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