GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Edn1 | increases abundance | EXP | | 6480464 | CTD | EDN1 protein results in increased abundance of Reactive Oxygen Species | PMID:16391241 PMID:22431579 | Edn1 | increases chemical synthesis | EXP | | 6480464 | CTD | EDN1 protein results in increased chemical synthesis of Reactive Oxygen Species | PMID:16271043 | Edn1 | multiple interactions | EXP | | 6480464 | CTD | acetovanillone inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species]; atrasentan inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species]; BQ 485 inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species] | PMID:16391241 PMID:22431579 | Edn1 | increases expression | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | Reactive Oxygen Species results in increased expression of EDN1 protein | PMID:11603923 | Edn1 | multiple interactions | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | Reactive Oxygen Species results in increased phosphorylation of and results in increased activity of EDN1 protein | PMID:11603923 | |
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