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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619788
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Acc ID: CHEBI:2639
Term: amiloride
Definition: A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.
Chemical ID: MESH:D000584
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc6decreases activityISOTrpc6 (Mus musculus)6480464CTDAmiloride results in decreased activity of TRPC6 proteinPMID:11179201
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