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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:25942
Term: peroxynitrous acid
Definition: A nitrogen oxoacid that has formula HNO3.
Chemical ID: MESH:D030421
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDPeroxynitrous Acid results in increased expression of BAX mRNA; Peroxynitrous Acid results in increased expression of BAX proteinPMID:20869986
Baxmultiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX protein]PMID:20869986
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