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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735801
Species: Homo sapiens
RGD Object: Gene
Symbol: ACTB
Name: actin beta
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACTBmultiple interactionsEXP 6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of and results in increased oxidation of ACTB mRNA; [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of ACTB mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of and results in increased oxidation of ACTB mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased expression of and results in increased oxidation of ACTB mRNAPMID:32699268 PMID:32845096
ACTBdecreases expressionISOActb (Rattus norvegicus)6480464CTDOzone results in decreased expression of ACTB mRNAPMID:16330353
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