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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69323
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Acc ID: CHEBI:2564
Term: aldrin
Definition: An organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with norbornadiene. A proinsecticide (by epoxidation of the non-chlorinated double bond to give dieldrin), it was widely used as an insecticide before being banned in the 1970s as a persistent organic pollutant.
Chemical ID: MESH:D000452
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Erbb3multiple interactionsISOERBB3 (Homo sapiens)6480464CTD[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNAPMID:19422813
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