A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke.
Chemical ID:
MESH:D015127
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
9,10-Dimethyl-1,2-benzanthracene results in increased expression of AHR mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of AHR protein
9,10-Dimethyl-1,2-benzanthracene binds to and results in increased activity of AHR protein; AHR protein promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDH13 mRNA]; betulin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AHR protein]
9,10-Dimethyl-1,2-benzanthracene binds to and results in increased activity of AHR protein; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in decreased expression of CXCL10 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of ADH7 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of AHRR mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of ALDH3A1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of ARL6IP5 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of BTG2 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CCL2 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CCNG1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CCNO mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CENPB mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CXCL5 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of DDIT4 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of DOK1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of FOSL1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of GCHFR mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of GPRC5A mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of IER3 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of INHBB mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of LPL mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of NFE2L2 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of NQO1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PGD mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PHLDA1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PHLDA3 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PTGS2 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PTX3 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of SPP1 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of SULF2 mRNA; [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of TIPARP mRNA; [AHR mRNA affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which results in decreased expression of CYP1A1; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of ARTN protein]; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of IL4RA]; AHR mRNA promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TSLP]; galangin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein]
9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein results in increased expression of CCL5 mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DAZL mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of DDX4 mRNA]; AHR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of PRDM1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein]; isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the localization of AHR protein]
