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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735778
Species: Mus musculus
RGD Object: Gene
Symbol: Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn1aaffects expressionISOSCN1A (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of SCN1A proteinPMID:20106945
Scn1adecreases expressionISOSCN1A (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of SCN1A mRNAPMID:21632981
Scn1aincreases expressionISOScn1a (Rattus norvegicus)6480464CTDAflatoxin B1 results in increased expression of SCN1A mRNAPMID:23630614
Scn1aincreases expressionISOSCN1A (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of SCN1A mRNAPMID:32234424
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