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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62281 Species: Mus musculus RGD Object: Gene Symbol: Ankrd1 Name: ankyrin repeat domain 1 (cardiac muscle)

Acc ID: CHEBI:2504 Term: aflatoxin B1 Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11. CasRN: 1162-65-8 Chemical ID: MESH:D016604

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:1348352	6480464	CTD	Aflatoxin B1 affects the expression of ANKRD1 protein	PMID:20106945
decreases expression	EXP		6480464	CTD	Aflatoxin B1 results in decreased expression of ANKRD1 mRNA	PMID:19770486
increases expression	ISO	RGD:1348352	6480464	CTD	Aflatoxin B1 results in increased expression of ANKRD1 mRNA	PMID:22100608