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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621391
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slco2b1
Name: solute carrier organic anion transporter family, member 2b1
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco2b1affects expressionISOSLCO2B1 (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of SLCO2B1 proteinPMID:20106945
Slco2b1decreases expressionISOSLCO2B1 (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of SLCO2B1 mRNAPMID:22100608 PMID:27153756
Slco2b1decreases expressionISOSlco2b1 (Mus musculus)6480464CTDAflatoxin B1 results in decreased expression of SLCO2B1 mRNAPMID:19770486
Slco2b1increases methylationISOSLCO2B1 (Homo sapiens)6480464CTDAflatoxin B1 results in increased methylation of SLCO2B1 genePMID:27153756
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