GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | decreases expression | EXP | | 6480464 | CTD | Aflatoxin B1 results in decreased expression of NFE2L2 protein | PMID:25154877 | Nfe2l2 | increases expression | EXP | | 6480464 | CTD | Aflatoxin B1 results in increased expression of NFE2L2 mRNA | PMID:33354967 | Nfe2l2 | increases response to substance | EXP | | 6480464 | CTD | NFE2L2 gene mutant form results in increased susceptibility to Aflatoxin B1 | PMID:27071940 | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | [Aflatoxin B1 co-treated with caryophyllene] results in increased expression of NFE2L2 protein; Benzopyrans inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 protein] | PMID:25154877 PMID:34506763 | Nfe2l2 | decreases activity | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Aflatoxin B1 results in decreased activity of NFE2L2 protein | PMID:30203046 | Nfe2l2 | decreases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Aflatoxin B1 results in decreased expression of NFE2L2 mRNA; Aflatoxin B1 results in decreased expression of NFE2L2 protein | PMID:35063475 | Nfe2l2 | decreases methylation | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in decreased methylation of NFE2L2 gene | PMID:27153756 | Nfe2l2 | increases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in increased expression of NFE2L2 protein | PMID:34089297 | Nfe2l2 | increases methylation | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in increased methylation of NFE2L2 intron | PMID:30157460 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 protein] | PMID:35063475 | |
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