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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Junb
Name: JunB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junbincreases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of JUNB mRNAPMID:25378103 PMID:33354967
Junbaffects expressionISOJUNB (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of JUNB proteinPMID:20106945
Junbdecreases expressionISOJUNB (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of JUNB mRNAPMID:28458013
Junbincreases expressionISOJUNB (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of JUNB mRNAPMID:21641981
Junbincreases expressionISOJunb (Mus musculus)6480464CTDAflatoxin B1 results in increased expression of JUNB mRNAPMID:19770486
Junbincreases methylationISOJUNB (Homo sapiens)6480464CTDAflatoxin B1 results in increased methylation of JUNB genePMID:28458013
Junbmultiple interactionsISOJUNB (Homo sapiens)6480464CTDdecitabine inhibits the reaction [Aflatoxin B1 results in decreased expression of JUNB mRNA]PMID:28458013
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